LIFE SCIENCES AND PHARMACOLOGY

[693ME]
a.a. 2025/2026

Full year

Frequency Mandatory

  • 6 CFU
  • 60 hours
  • italian
  • University campus of Gorizia
  • Obbligatoria
  • Oral Exam
  • SSD BIO/09, BIO/13, BIO/14
  • Core subjects
Curricula: COMMON

Structured into the following modules:

Syllabus

D1. Knowledge and understanding: At the end of the course the student must demonstrate knowledge of the fundamental principles of general and work-related physiology, aimed in particular at the prevention of occupational pathologies, as well as the general principles of applied biology, microbiology and pharmacology in order to predict a correct diagnostic path and suggest pharmacological hypotheses in the fight against infections.
D2. Ability to apply knowledge and understanding: At the end of the course the student must be able to apply the knowledge acquired in point D1 demonstrating understanding of the elements of biology, microbiology and pharmacology in order to be able to frame the most effective prevention and treatment strategies in individual infectious contexts. They must also be able to evaluate whether or not the adaptations necessary following particular work exposures fall within the allostatic compensation zone of the human organism and propose any changes to improve the environmental working conditions.
D3. Making judgement: Making judgement. The student must demonstrate the ability to use the skills acquired with independent judgment. He/she must be able to interpret pharmacological, microbiological data and physiological parameters, even in the case of particular occupational exposures.
D4. Communication skills. At the end of the course the student must be able to clearly explain the concepts acquired, and will be able to collaborate with the care team in their professional capacity.
D5. Learning ability: At the end of the course the student must be able to independently delve into the topics covered by consulting scientific journals and specialist texts in their professional field.

Basic knowledge relating to cellular and DNA structure, anatomy, physiology, biochemistry and biology

The course aims to provide the student with:
- the basis of cellular biology, the functional mechanisms of nuclear biomolecular processes, from the management of genetic information to the generation of specialized cell types.
- The basics of physiology of the human body: blood, lymph, cardiovascular system, respiratory system, gas exchange and transport, central and peripheral nervous system, thermoregulation, integumentary system, endocrine system, urinary system, digestive system.
- Work physiology: physiological responses and adaptations of workers in particular exposure scenarios, role of age, gender and underlying pathologies.
- Principles of pharmacology: pharmacokinetics: absorption, distribution, biotransformation and excretion of drugs; pharmacodynamics: focus on the role of proteins. Individual variability, side effects, drug interactions, drug addiction and substances of abuse.
- Principles of microbiology: biological risk in healthcare pursuant to current legislation, classification of microorganisms in relation to the characteristics of transmissibility, infectivity, pathogenicity and neutralizability. Aspects of primary and secondary prevention. Host susceptibility factors.

Biologia & Genetica - Donati, Stefani, Taddei - Anno 2019 o testi universitari di Biologia Cellulare e Molecolare purchè recenti
F Rossi, V Cuomo, C Riccardi, Farmacologia: principi di base e applicazioni terapeutiche, Ed. Minerva Medica
FISIOLOGIA UMANA-un approccio integrato, settima edizione, DeeUnglaub Silverthorn
ANATOMIA E FISIOLOGIA - M.P. McKinley et al - 2016 - Piccin
ANATOMIA E FISIOLOGIA - K.T. Patton, G.A. Thibodeau – 2011 – Elsevier
Microbiologia e microbiologia clinica. Per le professioni sanitarie e odontoiatria. Ediz. MyLab.
Material made available by teachers on the MS Teams platform.

Applied biology: Eukaryotes and Prokaryotes, genetic heritage, phases of the cell cycle, concepts of cell, tissue, organ, organism
Microbiology: types and characteristics of microorganisms pathogenic to humans, classification of danger, diagnostic tools and preventive aspects of the main infectious diseases.
Pharmacology: nature and types of drugs, pharmacokinetics and pharmacodynamics, inter-individual variations, side effects, drug addiction and substances of abuse.
Physiology: concept of homeostasis, body fluids, blood and its components, cardio-respiratory, urinary, integumentary systems, central nervous system, digestive system
Work Physiology: Cardiovascular, muscular, metabolic, circadian and skin responses and adaptations in relation to changing occupational exposure scenarios (work/mental load, extreme microclimate, activity at altitude and below sea level, gender, age, comorbidities).

Lectures, interactive lessons, audiovisual material aimed at better understanding the topics covered, group exercises on specific topics that will be presented by the students to the class

for any further specific needs, refer to the details of the individual module of interest

The learning of the program will be assessed through partial tests for each teaching module, by the individual teachers, through which the level of knowledge and competence achieved by the student, the mastery of the tools acquired and their contextualization will be ascertained.
The partial tests will consist of written tests made up of multiple choice questions and open questions on the topics covered, possibly also implemented through oral tests.
For details, refer to the specifications of each module.
Each module will be considered passed if the student has achieved a grade of ≥ 18/30.
The overall outcome of the integrated teaching will subsequently be recorded in an appeal specifically created for this purpose.

health and safety of healthcare workers
quality education