The aims of the course is to provide fundamental notions about the biological effects of exposure to ionising radiation in the environment and the workplace. The deterministic and stochastic effects of ionising radiation, and well as notions of radiotoxicology, will be discussed. Elements of health surveillance, health care and therapy for excessive exposure to ionising radiation will be presented. D1. Knowledge and understanding: At the end of the course, the student will be able to demonstrate knowledge of the rules and regulations governing professional practice in work activities involving exposure to ionising radiation and safe working practices relating to the correct use of collective and personal protective equipment. D2. Ability to apply knowledge and understanding: At the end of the course the student must be able to find, recognise and interpret a regulatory text and/or a guideline on safety in work activities involving exposure to ionising radiation D3: Making judgements: At the end of the course, the student must be able to analyse and propose choices for safety in work activities involving exposure to ionising radiation. D4: Communication skills: At the end of the course, the student must be able to demonstrate the concepts of knowledge and ability to understand safety in work activities involving exposure to ionising radiation. D5. Learning skills: By the end of the course, the student should be able to independently deepen the topics covered and also be able to transfer the concepts learned to subsequent courses.

Elelements of physics and epidemiology

Biological and health effects of ionising radiation. Radioprotection for workers and general population. Health surveillance of the radioprotection. Italian and EU legislation. Health Radioprotection (program) 1. Radiobiological foundations 1.1 Biological mechanisms 1.2 Molecular, cellular, and tissue effects 2. Deterministic effects 2.1 Acute effects: RAS 2.2 Chronic effects: radiodermitis, cataract, infertility 3. Stochastic effects 3.1 Somatic effects (leukemia, solid tumors) 3.2 Genetic effects 4. Role of the authorised physician 4.1 Health surveillance 4.2 fitness criteria for radiation exposure 4.3 prescribed radiation-induced diseases 5. Exposure to ionising radiation from natural sources (e.g. Radon)

Alessio, Apostoli: “Medicina del lavoro e Igiene Industriale per i tecnici della prevenzione nell’ambiente e nei luoghi di lavoro”. Piccin 2008

Health Radioprotection (program) 1. Radiobiological foundations 1.1 Biological mechanisms 1.2 Molecular, cellular, and tissue effects 2. Deterministic effects 2.1 Acute effects: RAS 2.2 Chronic effects: radiodermitis, cataract, infertility 3. Stochastic effects 3.1 Somatic effects (leukemia, solid tumors) 3.2 Genetic effects 4. Role of the authorised physician 4.1 Health surveillance 4.2 fitness criteria for radiation exposure 4.3 prescribed radiation-induced diseases. 5. Exposure to ionising radiation from natural sources (e.g. Radon)

Lectures.

The student's assessment involves a written test in which 19 multiple-choice and 4 open-ended questions on the topics covered in the course are proposed. Each correct multiple-choice answer will be awarded a mark of 1, each incorrect or incorrect answer a mark of 0. Each open question may be awarded a mark from 0 to 3 in relation to the appropriateness and exhaustiveness of the answer and clarity of exposition. The final mark for the examination is awarded by means of a mark expressed in thirtieths. In order to pass the examination (18/30), the student must demonstrate sufficient knowledge of the topics covered. In order to obtain the maximum mark (30/30 with distinction), the student must demonstrate excellent knowledge of all the topics covered in the course by answering all the questions correctly.

This course explores topics closely related to one or more goals of the United Nations 2030 Agenda for Sustainable Development (SDGs)